Sasha-Lee Dorfling-Jooste

Position: Lecturer

Department: Chemistry

Phone: +27(0)41 504 4285

Email: Sasha-Lee.Dorfling@mandela.ac.za

Sasha-Lee Dorfling-Jooste earned her Ph.D. in Chemistry from Nelson Mandela University (2017). Following several years of providing tutoring support to the chemistry department during her postgraduate studies, she became a member of the department in 2017. She devotes a significant portion of her time to her first-year chemistry students and is deeply committed to the field of chemical education. Her current area of research focuses on the use of fresh/living spirulina and its various bioactive compounds on cancer, diabetic and water purification studies. This research is conducted in collaboration with Spiruliving Institute where Sasha-Lee currently has a seat on the Board of Advisors. 

 

Areas of Expertise

  • Supramolecular chemistry – specifically in the field of Host-Guest chemistry
  • Designing effective chemical education modes
  • The use of Living Spirulina in cancer, diabetes and water purification studies. 

Education

  • PhD, Chemistry, 2017
  • MSc, Chemistry, 2014
  • BSc(Hons), Chemistry, 2013
 

Currently Teaching

  • CHGX101 – BSc (extended) General Chemistry
  • CHIX101 - BSc (extended) Inorganic Chemistry
  • CHOX101 - BSc (extended) Organic Chemistry
  • BVCV1X2 – Nursing Chemistry (extended)
  • YMES100 – Basic Medical Science
  • CHO420 – Pericyclic and Frontier Molecular Orbital Theory 
 

Selected Publications

1. HOST BEHAVIOUR OF RELATED COMPOUNDS, TETROL AND DMT, IN THE PRESENCE OF TWO DIFFERENT CLASSES OF AROMATIC GUEST COMPOUNDS
  • Author(s): Barton, Benita; de Jager, Lize; Dorfling, Sasha-Lee; Hosten, Eric; McCleland, Cedric; Pohl, Pieter
  • Journal: Tetrahedron
  • DOI: 10.1016/j.tet.2018.07.044
  • The graphical abstract supplied with this paper was selected to appear on the front cover of the next issue of Tetrahedron (issue, Vol.74/No.36), 
2. HOST COMPOUNDS (+)-(2R,3R)-1,1,4,4-TETRAPHENYLBUTANE-1,2,3,4-TETRAOL (TETROL) AND (2R,3R)-(−)-2,3-DIMETHOXY-1,1,4,4-TETRAPHENYLBUTANE-1,4-DIOL (DMT) WITH GUESTS O-, M- AND PTOLUIDINE: A COMPARATIVE INVESTIGATION
  • Author(s): Barton, Benita; Dorfling, Sasha-Lee; Hosten, Eric; Pohl, Pieter
  • Journal: Tetrahedron
  • DOI: 10.1016/j.tet.2018.04.039
3. HYDROGEN BONDING, THE DRIVING FORCE FOR INCREASED HOST SELECTIVITIES IN TWO-SOLVENT MIXED COMPLEXES OF TETROL COMPRISING BOTH FAVORED (ANILINE) AND DISFAVORED GUESTS (O-TOLUIDINE OR TOLUENE)
  • Author(s): Barton, Benita; Dorfling, Sasha-Lee; Hosten, Eric
  • Journal: Crystal Growth & Design
  • DOI: 10.1021/acs.cgd.8b00364
4. CYCLOHEXANONE-DRIVEN DISCRIMINATORY BEHAVIOUR CHANGE OF HOST COMPOUND (+)-(2R,3R)-TETROL FOR THE ISOMERIC METHYLCYCLOHEXANONE GUESTS
  • Author(s): Barton, Benita; Dorfling, Sasha-Lee; Hosten, Eric
  • Journal: Crystal Growth & Design
  • DOI: 10.1021/acs.cgd.7b01334